Callum Elder will be suspended for Wigan's Sunday afternoon clash with Bury at the DW Stadium.
The defender, on loan from Leicester, still has two games remaining on the three-match suspension he incurred following his dismissal at MK Dons on the opening day.
Paul Cook made 11 changes for the Carabao Cup in midweek and captain Sam Morsy, defender Dan Burn and Nick Powell, fitness permitting, should all return to the XI.
Shaun MacDonald (broken leg) and Reece James (foot) remain out while transfer-listed pair Max Power and Omar Bogle have not featured this season.
Bury will be without their captain Stephen Dawson after the midfielder was forced off against Sunderland in midweek.
Dawson was taken off on a stretcher with a knee injury that boss Lee Clark is hoping will only keep him out for weeks rather than months.
It further reduces the Shakers' numbers, with Jay O'Shea, Phil Edwards and Eoghan O'Connell all missing already due to knee injuries, and Danny Mayor out with a hip issue.
Joe Skarz (groin) and Tom Heardman (leg) are also missing but Clark insists Chris Maguire will be fine despite the thigh problem which kept him out of the team on Thursday.