Jewell said: "We're up against it, but we've worked on things this week and the players will be well briefed.
"We're not going to feel sorry for ourselves. We will have 11 players out there who will be committed, and we will see what we get out of the game.
"But we need everybody fit and available because we've injuries and a couple of suspensions."
Stephen Gerrard should be back for Liverpool after recovering from a knee injury, while Henri Camara is being rushed back from Egypt for the Latics.
Wigan (from): Pollitt, Jackson, De Zeeuw, Henchoz, Teale, Johansson, Kavanagh, Mahon, Francis, Scharner, Thompson, Bullard, Baines, Ziegler, Camara, Walsh.
Liverpool (from): Dudek, Finnan, Kromkamp, Carragher, Agger, Hyypia, Riise, Traore, Gerrard, Alonso, Hamann, Sissoko, Kewell, Morientes, Fowler, Cisse, Carson.
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